Recombinant AKR1B1 Monoclonal Antibody
Product Specifications
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 37 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
Abbreviation
AKR1B1
UniProt
P15121
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human AKR1B1 protein
Target
ALR; MGC; ALDR; AKR1B; AKR1B1; ADR; ALDR1; ALR2; AR; MGC1804; AKR1B 1; Aldehyde reductase; Aldehyde reductase 1; Aldo keto reductase family 1; aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; Aldose reductase; aldr 1; Lii5 2 CTCL tumor antigen; Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1; Low Km aldose reductase; member B1; member B1 (aldose reductase) ; member B1|aldose reductase|low Km aldose reductase
Clonality
Monoclonal
Clone
9D9
Conjugation
Unconjugated
Applications
WB; ICC/IF; IP
Field of Research
Signal Transduction; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; ICC/IF 1:20-1:100; IP 0.2-1 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Observed Molecular Weight
37 kDa
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items