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Recombinant AKR1B1 Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 37 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Abbreviation

AKR1B1

UniProt

P15121

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human AKR1B1 protein

Target

ALR; MGC; ALDR; AKR1B; AKR1B1; ADR; ALDR1; ALR2; AR; MGC1804; AKR1B 1; Aldehyde reductase; Aldehyde reductase 1; Aldo keto reductase family 1; aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; Aldose reductase; aldr 1; Lii5 2 CTCL tumor antigen; Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1; Low Km aldose reductase; member B1; member B1 (aldose reductase) ; member B1|aldose reductase|low Km aldose reductase

Clonality

Monoclonal

Clone

9D9

Conjugation

Unconjugated

Applications

WB; ICC/IF; IP

Field of Research

Signal Transduction; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; ICC/IF 1:20-1:100; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

35 kDa

Observed Molecular Weight

37 kDa

Isotype

IgG

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