Recombinant AK2/Adenylate kinase 2 Monoclonal Antibody
Product Specifications
Background
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 1.
Abbreviation
AK2
UniProt
P54819
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human AK2 protein
Target
ADK; KAD; Adenylate kinase isoenzyme; ATP-AMP transphosphorylase; AK2; ADK2; Adenylate kinase 2; Adenylate kinase isoenzyme 2; AK 2; ATP AMP transphosphorylase; ATP-AMP transphosphorylase 2; EC 2.7.4.3; KAD2; mitochondrial; mitochondrial
Clonality
Monoclonal
Clone
9D8
Conjugation
Unconjugated
Applications
WB; IHC-P
Field of Research
Cell Biology; Signal Transduction; Metabolism; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
26 kDa
Observed Molecular Weight
26 kDa
Isotype
IgG
Curated Selection
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