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Recombinant AK2/Adenylate kinase 2 Monoclonal Antibody

Product Specifications

Background

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 1.

Abbreviation

AK2

UniProt

P54819

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human AK2 protein

Target

ADK; KAD; Adenylate kinase isoenzyme; ATP-AMP transphosphorylase; AK2; ADK2; Adenylate kinase 2; Adenylate kinase isoenzyme 2; AK 2; ATP AMP transphosphorylase; ATP-AMP transphosphorylase 2; EC 2.7.4.3; KAD2; mitochondrial; mitochondrial

Clonality

Monoclonal

Clone

9D8

Conjugation

Unconjugated

Applications

WB; IHC-P

Field of Research

Cell Biology; Signal Transduction; Metabolism; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

26 kDa

Observed Molecular Weight

26 kDa

Isotype

IgG

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