Recombinant KRT5 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q10.
Abbreviation
KRT5
UniProt
P13647
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the center region of the human KRT5
Target
EBS; KRT; keratin; KRT5; CK5; DDD; DDD1; EBS2; K5; KRT5A; keratin 5;58 kDa cytokeratin; basic; CK-5; Cytokeratin5; Cytokeratin-5; Dowling-Meara/Kobner/Weber-Cockayne types) ; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; gene 5; K2C5; keratin 5 (epidermolysis bullosa simplex; keratin complex 2; Keratin5; Keratin-5; KRT 5; type II cytoskeletal 5; Type-II keratin Kb5
Clonality
Monoclonal
Clone
12F4
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Signal Transduction
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/31k19bze
Product MSDS
https://789.bio/eb/CzRWKnVi
Isotype
IgG
Curated Selection
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