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Recombinant Cytokeratin 5/KRT5 Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q10.

Abbreviation

KRT5

UniProt

P13647

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the center region of the Human Cytokeratin 5/KRT5

Target

EBS; KRT; keratin; KRT5; CK5; DDD; DDD1; EBS2; K5; KRT5A; keratin 5;58 kDa cytokeratin; basic; CK-5; Cytokeratin5; Cytokeratin-5; Dowling-Meara/Kobner/Weber-Cockayne types) ; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; gene 5; K2C5; keratin 5 (epidermolysis bullosa simplex; keratin complex 2; Keratin5; Keratin-5; KRT 5; type II cytoskeletal 5; Type-II keratin Kb5

Clonality

Monoclonal

Clone

12F3

Conjugation

Unconjugated

Applications

WB; ICC/IF

Field of Research

Signal Transduction

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; ICC/IF 1:20-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

62 kDa

Observed Molecular Weight

62 kDa

Isotype

IgG

Curated Selection

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