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Recombinant SerpinG1/C1 inhibitor/C1IN Monoclonal Antibody

Product Specifications

Background

This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C2s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE) . Alternative splicing results in multiple transcript variants encoding the same isoform.

Abbreviation

SerpinG1

UniProt

P05155

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human SerpinG1 protein

Target

SERPING; Serpin G; HAE; SERPING1; C1IN; C1INH; C1NH; HAE1; HAE2; C1 Esterase Inhibitor; C1 Inh; C1-Inhibiting Factor; Plasma Protease C1 Inhibitor; Serpin G1

Clonality

Monoclonal

Clone

11G4

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Cardiovascular; Immunology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 0.5-2 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

55 kDa

Observed Molecular Weight

71 kDa

Isotype

IgG

Available Sizes

Curated Selection

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