Recombinant PIGR Monoclonal Antibody
Product Specifications
Background
The human polymeric immunoglobulin receptor (pIgR; also known as membrane secretory component) is an approximately 100 kDa type I transmembrane glycoprotein that is synthesized as a 764 amino acid (aa) precursor. It includes a signal sequence (aa 1-18), an extracellular region (aa 19-638), a transmembrane segment (aa 639-661), and a cytoplasmic domain (aa 662-764) . The extracellular region consists of five Ig-like domains and a sixth non-Ig domain that connects to the membrane region. pIgR is expressed on secretory epithelial cells of exocrine tissues. Immunoglobulin isotypes consist of two heavy (H) and two light (L) chains. F
Abbreviation
PIGR
UniProt
P01833
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human PIGR protein
Target
Hepatocellular carcinoma-associated protein TB; PIGR; Polymeric immunoglobulin receptor; Hepatocellular carcinoma-associated protein TB6; Secretory component; Poly-Ig receptor
Clonality
Monoclonal
Clone
12G8
Conjugation
Unconjugated
Applications
IHC-P; ICC/IF
Field of Research
Immunology
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:50-1:200; ICC/IF 1:20-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/59zthxc1
Product MSDS
https://789.bio/eb/gewbXajH
Isotype
IgG
Available Sizes
Curated Selection
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