Recombinant PIGR Monoclonal Antibody

The human polymeric immunoglobulin receptor (pIgR; also known as membrane secretory component) is an approximately 100 kDa type I transmembrane glycoprotein that is synthesized as a 764 amino acid (aa) precursor. It includes a signal sequence (aa 1-18), an extracellular region (aa 19-638), a transmembrane segment (aa 639-661), and a cytoplasmic domain (aa 662-764) . The extracellular region consists of five Ig-like domains and a sixth non-Ig domain that connects to the membrane region. pIgR is expressed on secretory epithelial cells of exocrine tissues. Immunoglobulin isotypes consist of two heavy (H) and two light (L) chains. F

Hepatocellular carcinoma-associated protein TB; PIGR; Polymeric immunoglobulin receptor; Hepatocellular carcinoma-associated protein TB6; Secretory component; Poly-Ig receptor

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.