Recombinant ALDH7A1 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 23g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.
Abbreviation
ALDH7A1
UniProt
P49419
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human ALDH7A1 protein
Target
ATQ; ALDH7A; ALDH7A1; ATQ1; EPD; PDE
Clonality
Monoclonal
Clone
10F11
Conjugation
Unconjugated
Applications
FCM; ICC/IF
Field of Research
Signal Transduction; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
ICC/IF 1:20-1:100; FCM 1:25-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG
Curated Selection
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