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Recombinant BID Monoclonal Antibody

Product Specifications

Background

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) ; CASP5 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Abbreviation

BID

UniProt

P55957

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human BID protein

Target

BID; FP497; BH3-Interacting Domain Death Agonist; p22 BID

Clonality

Monoclonal

Clone

6A2

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Cell Biology; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 0.5-2 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

22 kDa

Observed Molecular Weight

22 kDa

Isotype

IgG

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