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Recombinant MICB Monoclonal Antibody

Product Specifications

Background

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Abbreviation

MICB

UniProt

Q29980

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human MICB protein

Target

PERB; MICB; PERB11.2; MHC class I polypeptide-related sequence B

Clonality

Monoclonal

Clone

6A1

Conjugation

Unconjugated

Applications

WB

Field of Research

Immunology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

40 kDa

Observed Molecular Weight

67 kDa

Isotype

IgG

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