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Recombinant 4E-BP1/EIF4EBP1 Monoclonal Antibody

Product Specifications

Background

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Abbreviation

EIF4EBP1

UniProt

Q13541

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human 4E-BP1 / EIF4EBP1 protein

Target

4EBP; eIF4E binding protein; eukaryotic translation initiation factor 4E-binding protein;4E-BP; EIF4EBP; EIF4EBP1;4E-BP1;4EBP1; BP-1; PHAS-I; eukaryotic translation initiation factor 4E-binding protein 1; BP 1; eIF4E binding protein 1; eIF4E-binding protein 1; PHASI; Phosphorylated heat- and acid-stable protein regulated by insulin 1;4EBP1;4E-BP1; BP-1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I

Clonality

Monoclonal

Clone

2C3

Conjugation

Unconjugated

Applications

ICC/IF

Field of Research

Epigenetics and Nuclear Signaling; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:20-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

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