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Recombinant AFP/alpha-fetoprotein Monoclonal Antibody

Product Specifications

Background

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Abbreviation

AFP

UniProt

P02771

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human AFP / alpha-fetoprotein protein

Target

AFPD; FETA; HPAFP; AFP; Alpha fetoglobulin; Alpha fetoprotein; Alpha fetoprotein precursor; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; Hereditary persistence of; Hereditary persistence of alpha fetoprotein; included; oralpha fetal protein

Clonality

Monoclonal

Clone

8D2

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Cardiovascular; Cancer; Developmental Biology; Kits; Lysates; Other

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 0.5-2 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

68 kDa

Observed Molecular Weight

68 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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