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Recombinant Ly108/SLAMF6 Monoclonal Antibody

Product Specifications

Background

NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.

Abbreviation

SLAMF6

UniProt

Q96DU3

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human Ly108 / SLAMF6 protein

Target

UNQ; SLAM Family Member; SLAMF; SLAMF6; CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000; Activating NK Receptor; NK-T-B-Antigen; SLAM Family Member 6; UNQ6123; PRO20080; NTB-A; KAL1; Ly108

Clonality

Monoclonal

Clone

5A11

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Immunology

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:100-1:500

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG

Available Sizes

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