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Recombinant CD55/DAF Monoclonal Antibody

Product Specifications

Background

CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI) -anchored single chain glycoprotein also known as decay-accelerating factor (DAF) . It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.

Abbreviation

CD55

UniProt

P08174

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human CD55 protein

Target

CD55; CR; CROM; DAF; TC; Complement Decay-Accelerating factor; CD 55; CD55 antigen; CD55 Cromer blood group system; CD55 molecule; CD55 molecule (Cromer blood group) ; Cd55a; Complement decay accelerating factor; Cromer Blood Group antigen; Cromer blood group system; Cromer blood group system) ; Daf1; Daf-GPI; Dcay accelerating factor for complement (CD55; Decay accelarating factor 1; Decay accelerating factor (GPI-form) ; Decay Accelerating Factor for Complement; decay accelerating factor for complement (Cromer blood group) ; Decay accelerating factor GPI-form; Decay accelerating factor soluble-form; GPI-anchored; GPI-DAF; isoform CRA_a

Clonality

Monoclonal

Clone

5A2

Conjugation

Unconjugated

Applications

FCM; ICC/IF

Field of Research

Immunology

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:10-1:40; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://789.bio/ea/rj4gb7gr

Product MSDS

https://789.bio/eb/NwjABq7j

Isotype

IgG

Available Sizes

Curated Selection

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