Recombinant CD38 Monoclonal Antibody
Product Specifications
Background
CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD (P) + into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose . CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
Abbreviation
CD38
UniProt
P28907
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human CD38 protein
Target
CADPr hydrolase; ADP-ribosyl cyclase; cyclic ADP-ribose hydrolase; Acute lymphoblastic leukemia cells antigen CD; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; CD38; ADPRC 1; ADPRC1; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADP-ribosyl cyclase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; ADP-ribosyl; T10; cyclase;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1 (ADPRC 1) ; Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1) ; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10; ADP ribosyl cyclase 1; ADP ribosyl cyclase/cyclic ADP-ribose hydrolase; CD 38; CD38 antigen (p45) ; Cd38-rs1; Cyclic ADP ribose hydrolase 1; Ecto nicotinamide adenine dinucleotide glycohydrolase; I19 (mouse) ; Lymphocyte differentiation antigen CD38; NAD (+) nucleosidase; NIM-R5 antigen; NIMR5 antigen (mouse) ; OTTHUMP00000158633; OTTHUMP00000217743
Clonality
Monoclonal
Clone
3P11
Conjugation
Unconjugated
Applications
WB; IP
Field of Research
Immunology; Stem Cells; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:2000-1:10000; IP 1-5 µL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://789.bio/ea/iaxmdf07
Product MSDS
https://789.bio/eb/YYS49wUX
Calculated Molecular Weight
34 kDa
Observed Molecular Weight
45 kDa
Isotype
IgG
Curated Selection
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