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Recombinant CD27/TNFRSF7 Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

Abbreviation

CD27

UniProt

P26842

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant Human CD27/TNFRSF7 Protein

Target

S152. LPFS; T-cell activation antigen CD; TNFRSF; S152.LPFS; CD27; S152; S152. LPFS2; T14; TNFRSF7; Tp55; S152.LPFS2; CD27L receptor; T-cell activation antigen CD27; S152; TNFRSF7; CD 27; CD27 antigen; CD27 molecule; LPFS2; MGC20393; OTTHUMP00000238557; T cell activation antigen CD27; T cell antivation antigen S152; TNFRSF 7; TNFSF7; Tp 55; Tumor necrosis factor receptor superfamily member 7

Clonality

Monoclonal

Clone

2B8

Conjugation

Unconjugated

Applications

WB

Field of Research

Immunology; Cancer; Stem Cells

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

29 kDa

Observed Molecular Weight

65 kDa

Isotype

IgG

Curated Selection

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