Isovaleryl-CoA dehydrogenase/IVD Monoclonal Antibody

Product Specifications

Background

Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

IVD

UniProt

P26440

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human Isovaleryl-CoA dehydrogenase / IVD protein

Target

ACAD; IVD; ACAD2; FLJ12715; FLJ34849; Isovaleryl CoA dehydrogenase; Isovaleryl Coenzyme A dehydrogenase; Isovaleryl-CoA dehydrogenase; mitochondrial

Clonality

Monoclonal

Clone

13B6

Conjugation

Unconjugated

Applications

WB; FCM; ICC/IF; IP

Field of Research

Signal Transduction; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; FCM 1:100-1:500; ICC/IF 1:100-1:500; IP 0.1-0.5 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.