CLPS Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
Abbreviation
CLPS
UniProt
P04118
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CLPS Protein
Target
CLPS; colipase; COL; Colipase pancreatic; Pancreatic colipase preproprotein
Clonality
Monoclonal
Clone
12B8
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Cardiovascular; Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:100-1:500
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG1
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