PGDH/PHGDH Monoclonal Antibody
Product Specifications
Background
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
Abbreviation
PHGDH
UniProt
O43175
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human PGDH / PHGDH protein
Target
HEL-S; PHGDH;3-PGDH;3PGDH; HEL-S-113; NLS; NLS1; PDG; PGAD; PGD; PGDH; PHGDHD; SERA; PGDH3
Clonality
Monoclonal
Clone
11B11
Conjugation
Unconjugated
Applications
FCM; ICC/IF
Field of Research
Signal Transduction; Neuroscience; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
ICC/IF 1:20-1:100; FCM 1:25-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG2b
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items