Mesothelin/MSLN Monoclonal Antibody
Product Specifications
Background
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Abbreviation
MSLN
UniProt
Q13421
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human Mesothelin/MSLN Protein
Target
CAK; MSLN; MPF; SMRP; CAK1; CAK1 antigen; Megakaryocyte potentiating factor; mesothelin; Pre-pro-megakaryocyte-potentiating factor; SMR; soluble MPF mesothelin related protein; CAK 1; C-ERC/mesothelin; C-ERC/MSLN; cleaved form; Mesothelin isoform 1 precursor; N-ERC/mesothelin; N-ERC/MSLN; Pre pro megakaryocyte potentiating factor
Clonality
Monoclonal
Clone
11B8
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Tags & Cell Markers; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:30-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG1
Frequently Asked Questions
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