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RhoA Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

Abbreviation

RHOA

UniProt

P61586

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human RhoA protein

Target

ARH; RHOH; ARH12; ARHA; RHO12; RHOH12; Rho; RHOA; EDFAOB; ARH12; EDFAOB; RHO12; RHOH12; Aplysia ras related homolog 12; H 12; H12; Oncogene RHO H12; ras homolog family member A; Ras homolog gene family member A; Rho A; Rho cDNA clone 12; RHO H12; Small GTP binding protein Rho A; Transforming protein Rho A; Transforming protein RhoA

Clonality

Monoclonal

Clone

11A2

Conjugation

Unconjugated

Applications

FCM; ICC/IF

Field of Research

Signal Transduction; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:20-1:100; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG2a

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