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CD68 Monoclonal Antibody

Product Specifications

Background

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Abbreviation

CD68

UniProt

P34810

Host

Mouse

Reactivity

Human; Cynomolgus

Immunogen

Recombinant Human CD68 Protein

Target

SRD; LAMP; DKFZp686M; MACROPHAGE ANTIGEN CD; CD68 antigenmacrophage antigen CD; Scavenger receptor class D member; SR-D; SCARD; CD68; GP110; LAMP4; SCARD1; CD 68; CD68 antigen; CD68 antigenmacrophage antigen CD68; CD68 molecule; DKFZp686M18236; gp11; MACROPHAGE ANTIGEN CD68; Macrophage antigen CD68 (microsialin) ; Macrosialin; Scavenger receptor class D member 1; SRD1; SR-D1; gp110; CD 68; CD68; CD68 antigen; CD68 molecule; CD68; DKFZp686M18236; gp11; Gp110; LAMP4; Macrophage antigen CD68 (microsialin) ; MACROPHAGE ANTIGEN CD68; Macrosialin; SCARD1; Scavenger receptor class D member 1

Clonality

Monoclonal

Clone

7A12

Conjugation

Unconjugated

Applications

IHC-P; FCM

Field of Research

Immunology

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:30-1:100; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG1

Frequently Asked Questions

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