BID Monoclonal Antibody
Product Specifications
Background
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) ; CASP5 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Abbreviation
BID
UniProt
P55957
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human BID protein
Target
BID; FP497; BH3-Interacting Domain Death Agonist; p22 BID
Clonality
Monoclonal
Clone
5C8
Conjugation
Unconjugated
Applications
WB; FCM; ICC/IF
Field of Research
Cell Biology; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000; FCM 1:25-1:100; ICC/IF 1:20-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
22 kDa
Observed Molecular Weight
22 kDa
Isotype
IgG1
Available Sizes
Curated Selection
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