NRG1-beta 1 Monoclonal Antibody

Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis.

NRG; MST; HRG1-beta; NRG1-beta; Pro-neuregulin; Neuregulin-1 beta; ARIA; EGF; GGF2; HRG; HRG1; HRG1-beta 1; MST131; Neuregulin-1 beta 1; NRG1-beta 1; Pro-neuregulin-1; GGF; HGL; HRGA; NDF; SMDF; NRG1; Acetylcholine receptor-inducing activity; alpha (45kD; Breast cancer cell differentiation factor p45; CHICK; ERBB2 p185-activator) ; Glial growth factor; Heregulin; homolog of; membrane-bound isoform; Neu differentiation factor; Neuregulin 1; neuregulin 1 type IV beta 1a; neuregulin 1 type IV beta 3; Neuregulin-1; NRG 1; NRG1-IT2; OTTHUMP00000225398; OTTHUMP00000225419; OTTHUMP00000225420; OTTHUMP00000225421; OTTHUMP00000225422; OTTHUMP00000225477; OTTHUMP00000225545; OTTHUMP00000230603; OTTHUMP00000230605; ProNRG1; Pro-NRG1; Sensory and motor neuron-derived factor

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.