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14-3-3 eta/YWHAH Monoclonal Antibody

Product Specifications

Background

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 2' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder.

Abbreviation

YWHAH

UniProt

Q04917

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human 14-3-3 eta / YWHAH protein

Target

YWHA; YWHAH; YWHA1

Clonality

Monoclonal

Clone

4B7

Conjugation

Unconjugated

Applications

WB; IP

Field of Research

Signal Transduction; Stem Cells

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IP 1-4 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

28 kDa

Observed Molecular Weight

30 kDa

Isotype

IgG1

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