Mcl-1 Monoclonal Antibody

Product Specifications

Background

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 0) promote apoptosis and are death-inducing.

Abbreviation

MCL1

UniProt

Q07820

Host

Mouse

Reactivity

Human

Immunogen

A synthetic peptide corresponding to the center region of the Human Mcl-1

Target

BCL2L; bcl2-L; MCL; MCL1; BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT; Bcl 2 related protein EAT/mcl1; BCL2 related; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; Induced myeloid leukemia cell differentiation protein Mcl 1; Induced myeloid leukemia cell differentiation protein Mcl-1; MCL 1; MGC104264; MGC1839; Myeloid Cell Leukemia 1; Myeloid cell leukemia ES; Myeloid cell leukemia sequence 1; Myeloid cell leukemia sequence 1 BCL2 related; Myeloid cell leukemia sequence 1 isoform 1; OTTHUMP00000032794; OTTHUMP00000032795

Clonality

Monoclonal

Clone

4B4

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Cell Biology; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:20-1:80

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.