Mcl-1 Monoclonal Antibody
Product Specifications
Background
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 0) promote apoptosis and are death-inducing.
Abbreviation
MCL1
UniProt
Q07820
Host
Mouse
Reactivity
Human
Immunogen
A synthetic peptide corresponding to the center region of the Human Mcl-1
Target
BCL2L; bcl2-L; MCL; MCL1; BCL2L3; EAT; MCL1-ES; MCL1L; MCL1S; Mcl-1; TM; bcl2-L-3; mcl1/EAT; Bcl 2 related protein EAT/mcl1; BCL2 related; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; Induced myeloid leukemia cell differentiation protein Mcl 1; Induced myeloid leukemia cell differentiation protein Mcl-1; MCL 1; MGC104264; MGC1839; Myeloid Cell Leukemia 1; Myeloid cell leukemia ES; Myeloid cell leukemia sequence 1; Myeloid cell leukemia sequence 1 BCL2 related; Myeloid cell leukemia sequence 1 isoform 1; OTTHUMP00000032794; OTTHUMP00000032795
Clonality
Monoclonal
Clone
4B4
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Cell Biology; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:20-1:80
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG1
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