SULT2A1/STD Monoclonal Antibody
Product Specifications
Background
Hydroxysteroid sulfotransferase (SULT2A1) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.
Abbreviation
SULT2A1
UniProt
Q06520
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human SULT2A1 protein
Target
Sulfotransferase 2A; Sult2a; Bile Salt Sulfotransferase; Dehydroepiandrosterone Sulfotransferase; DHEAS; DHEA-ST; Hydroxysteroid Sulfotransferase; ST2; ST2A1; ST2A3; Sulfotransferase 2A1; HST; STD; SULT2A1; Alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotranasferase 2A1; dehydroepiandrosterone-preferring; DHEA ST; DHEA sulfotranasferase; EC 2.8.2.14; hSTa; member 1; sulfotranasferase; Sulfotransferase family 2A; Sulfotransferase family cytosolic 2A dehydroepiandrosterone (DHEA) preferring member 1
Clonality
Monoclonal
Clone
3G6
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
34 kDa
Observed Molecular Weight
35 kDa
Isotype
IgG1
Curated Selection
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