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SULT2A1/STD Monoclonal Antibody

Product Specifications

Background

Hydroxysteroid sulfotransferase (SULT2A1) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. SULT2A1 is a sulfo-conjugating phase II enzyme expressed at very high levels in the liver and intestine, the two major first-pass metabolic tissues, and in the steroidogenic adrenal tissue. SULT2A1 acts preferentially on the hydroxysteroids dehydroepiandrosterone, testosterone/dihydrotestosterone, and pregnenolone and on cholesterol-derived amphipathic sterol bile acids.

Abbreviation

SULT2A1

UniProt

Q06520

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human SULT2A1 protein

Target

Sulfotransferase 2A; Sult2a; Bile Salt Sulfotransferase; Dehydroepiandrosterone Sulfotransferase; DHEAS; DHEA-ST; Hydroxysteroid Sulfotransferase; ST2; ST2A1; ST2A3; Sulfotransferase 2A1; HST; STD; SULT2A1; Alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotranasferase 2A1; dehydroepiandrosterone-preferring; DHEA ST; DHEA sulfotranasferase; EC 2.8.2.14; hSTa; member 1; sulfotranasferase; Sulfotransferase family 2A; Sulfotransferase family cytosolic 2A dehydroepiandrosterone (DHEA) preferring member 1

Clonality

Monoclonal

Clone

3G6

Conjugation

Unconjugated

Applications

WB

Field of Research

Signal Transduction; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

34 kDa

Observed Molecular Weight

35 kDa

Isotype

IgG1

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