PDK/PDZ binding kinase/TOPK Monoclonal Antibody
Product Specifications
Background
This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.
Abbreviation
PBK
UniProt
Q96KB5
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human PBK protein
Target
HEL; Nori; PBK; CT84; HEL164; Nori-3; SPK; TOPK; PDZ binding kinase
Clonality
Monoclonal
Clone
5D13
Conjugation
Unconjugated
Applications
WB
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Signal Transduction; Cancer
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
36 kDa
Observed Molecular Weight
38 kDa
Isotype
IgG1
Available Sizes
Curated Selection
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