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PDK/PDZ binding kinase/TOPK Monoclonal Antibody

Product Specifications

Background

This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.

Abbreviation

PBK

UniProt

Q96KB5

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human PBK protein

Target

HEL; Nori; PBK; CT84; HEL164; Nori-3; SPK; TOPK; PDZ binding kinase

Clonality

Monoclonal

Clone

5D13

Conjugation

Unconjugated

Applications

WB

Field of Research

Cell Biology; Epigenetics and Nuclear Signaling; Signal Transduction; Cancer

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36 kDa

Observed Molecular Weight

38 kDa

Isotype

IgG1

Available Sizes

Curated Selection

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