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CD163 Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Abbreviation

CD163

UniProt

Q86VB7

Host

Mouse

Reactivity

Human

Immunogen

E. coli-derived Human CD163 fragment

Target

GHI/; SCARI; CD163; M130; MM130; SCARI1; ED2 (rat) ; GHI/61; Hemoglobin/Haptoglobin Complex Receptor; macrophage-associated antigen; p155; RM3/1; GHI/61

Clonality

Monoclonal

Clone

9D12

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Immunology; Cardiovascular

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:2000-1:10000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG1

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