CD163 Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Abbreviation
CD163
UniProt
Q86VB7
Host
Mouse
Reactivity
Human
Immunogen
E. coli-derived Human CD163 fragment
Target
GHI/; SCARI; CD163; M130; MM130; SCARI1; ED2 (rat) ; GHI/61; Hemoglobin/Haptoglobin Complex Receptor; macrophage-associated antigen; p155; RM3/1; GHI/61
Clonality
Monoclonal
Clone
9D12
Conjugation
Unconjugated
Applications
IHC-P
Field of Research
Immunology; Cardiovascular
Purification
Protein A
Concentration
1 mg/mL
Dilution
IHC-P 1:2000-1:10000
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG1
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