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USP7/HAUSP Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM24, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.

Abbreviation

USP7

UniProt

Q93009

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human USP7 / HAUSP protein

Target

TEF; USP; USP7; HAUSP; TEF1

Clonality

Monoclonal

Clone

9D5

Conjugation

Unconjugated

Applications

IHC-P

Field of Research

Cell Biology; Microbiology; Cancer; Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

1 mg/mL

Dilution

IHC-P 1:50-1:200

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG2a

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