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FGF2 Monoclonal Antibody

Product Specifications

Background

FGF basic, also known as FGF-2 and HBGF-2, is a member of the FGF family of mitogenic proteins. FGF basic is widely expressed and affects diverse aspects of embryonic development by regulating cell proliferation, differentiation, and survival. Various N-terminal extensions affect localization of FGF basic in cellular compartments but do not affect biological activity. Binding of FGF to heparin or cell surface heparan sulfate proteoglycans is necessary for binding of FGF to high affinity FGF receptors. Mature human FGF basic shares greater than 96% aa sequence identity with bovine, mouse, and rat FGF basic.

Abbreviation

FGF2

UniProt

P09038

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human FGF2 Protein

Target

HBGF; FGF; BFGF; FGF-2; FGFB; HBGF-2; Basic FGF; FGF2; Basic Fibroblast Growth Factor; B-FGF; FGF-β; Fibroblast Growth Factor 2; heparin-binding growth factor 2; prostatropin; BFGF; B-FGF; FGF-2; FGFB; fibroblast growth factor 2; HBGF-2; heparin-binding growth factor 2; prostatropin; basic; Basic fibroblast growth factor bFGF; FGF 2; FGF B; FGF2 basic; Fibroblast growth factor; Fibroblast growth factor 2 (basic) ; HBGF 2; HBGF2; HBGH 2; HBGH2; Heparin binding growth factor 2 precursor; heparin-binding growth factor 2; FGF-β

Clonality

Monoclonal

Clone

6H10

Conjugation

Unconjugated

Applications

WB

Field of Research

Cardiovascular; Signal Transduction; Neuroscience; Stem Cells; Cancer; Developmental Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

31 kDa

Observed Molecular Weight

17-30 kDa

Isotype

IgG1

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