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BMP-4 Monoclonal Antibody

Product Specifications

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.

Abbreviation

BMP4

UniProt

P12644

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human BMP-4 protein

Target

OFC; DVR; MGC; ZGC; Bone morphogenetic protein; zbmp; MCOPS; BMP; BMP4; BMP2B; BMP2B1; MCOPS6; OFC11; ZYME; BMP 2B; BMP 4; BMP-2B; BMP-4; Bone morphogenetic protein 2B; Bone morphogenetic protein 4; MGC100779; zbmp-4; zgc:100779; DVR4

Clonality

Monoclonal

Clone

11A8

Conjugation

Unconjugated

Applications

FCM; ICC/IF

Field of Research

Cardiovascular; Signal Transduction; Stem Cells; Cancer; Developmental Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:20-1:100; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgM

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