BMP-4 Monoclonal Antibody
Product Specifications
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.
Abbreviation
BMP4
UniProt
P12644
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human BMP-4 protein
Target
OFC; DVR; MGC; ZGC; Bone morphogenetic protein; zbmp; MCOPS; BMP; BMP4; BMP2B; BMP2B1; MCOPS6; OFC11; ZYME; BMP 2B; BMP 4; BMP-2B; BMP-4; Bone morphogenetic protein 2B; Bone morphogenetic protein 4; MGC100779; zbmp-4; zgc:100779; DVR4
Clonality
Monoclonal
Clone
11A8
Conjugation
Unconjugated
Applications
FCM; ICC/IF
Field of Research
Cardiovascular; Signal Transduction; Stem Cells; Cancer; Developmental Biology
Purification
Protein A
Concentration
1 mg/mL
Dilution
ICC/IF 1:20-1:100; FCM 1:25-1:100
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgM
Curated Selection
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