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14-3-3 beta/YWHAB Monoclonal Antibody

Product Specifications

Background

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC22 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

Abbreviation

YWHAB

UniProt

P31946

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human 14-3-3 beta / YWHAB protein

Target

Protein kinase C inhibitor protein; HEL-S; Protein; YWHAB; GW128; HEL-S-1; HS1; KCIP-1; YWHAA;14 3 3 alpha;14 3 3 protein beta/alpha;14-3-3 protein beta/alpha;1433B; Brain protein 14 3 3 beta isoform; HS 1; KCIP1; N-terminally processed; Protein 1054; Protein kinase C inhibitor protein 1

Clonality

Monoclonal

Clone

10F9

Conjugation

Unconjugated

Applications

FCM; ICC/IF

Field of Research

Neuroscience; Signal Transduction; Stem Cells; Cell Biology

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:20-1:100; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG2b

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