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OSMR/IL31RB Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 28 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Abbreviation

OSMR

UniProt

Q99650

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human OSMR protein

Target

PLCA; OSMR; IL-31R-beta; IL-31RB; OSMRB; PLCA1; IL-31 Receptor Subunit Beta; IL-31R Subunit Beta; Interleukin-31 Receptor Subunit Beta; Oncostatin-M specific receptor subunit beta; Oncostatin-M-Specific Receptor Subunit Beta

Clonality

Monoclonal

Clone

10F7

Conjugation

Unconjugated

Applications

IP

Field of Research

Immunology; Signal Transduction; Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

1 mg/mL

Dilution

IP 0.5-2 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG1

Available Sizes

Curated Selection

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