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NME1/NDKA Monoclonal Antibody

Product Specifications

Background

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME1), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Abbreviation

NME1

UniProt

P15531

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human NME1 / NDKA protein

Target

NME; Metastasis Inhibition Factor nm; NM23-H; NME1; AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1; Granzyme A-Activated DNase; Metastasis Inhibition Factor nm23; NDK A; NDP Kinase A; Nucleoside Diphosphate Kinase A; Tumor Metastatic Process-Associated Protein; drosophila; Granzyme A activated DNase; GZMA activated DNase; homolog 1; homolog of; included; NM23 long variant; NM23H1B; NM23-M1; NME/NM23 nucleoside diphosphate kinase 1; NME1-NME2 spliced read-through transcript; Nonmetastatic cells 1; Non-metastatic cells 1; Nonmetastatic protein 23; protein (NM23A) expressed in; protein expressed in

Clonality

Monoclonal

Clone

6A9

Conjugation

Unconjugated

Applications

FCM; ICC/IF

Field of Research

Epigenetics and Nuclear Signaling

Purification

Protein A

Concentration

1 mg/mL

Dilution

ICC/IF 1:20-1:100; FCM 1:25-1:100

Buffer

0.2 μm filtered solution in 20 mM MES, 100 mM NaCl, 10% Trehalose, 0.02% Tween 80, pH 6.0

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Isotype

IgG1

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