NME1/NDKA Monoclonal Antibody
Product Specifications
Background
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME1), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Abbreviation
NME1
UniProt
P15531
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human NME1 / NDKA protein
Target
NME; Metastasis Inhibition Factor nm; NM23-H; NME1; AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1; Granzyme A-Activated DNase; Metastasis Inhibition Factor nm23; NDK A; NDP Kinase A; Nucleoside Diphosphate Kinase A; Tumor Metastatic Process-Associated Protein; drosophila; Granzyme A activated DNase; GZMA activated DNase; homolog 1; homolog of; included; NM23 long variant; NM23H1B; NM23-M1; NME/NM23 nucleoside diphosphate kinase 1; NME1-NME2 spliced read-through transcript; Nonmetastatic cells 1; Non-metastatic cells 1; Nonmetastatic protein 23; protein (NM23A) expressed in; protein expressed in
Clonality
Monoclonal
Clone
6A9
Conjugation
Unconjugated
Applications
FCM; ICC/IF
Field of Research
Epigenetics and Nuclear Signaling
Purification
Protein A
Concentration
1 mg/mL
Dilution
ICC/IF 1:20-1:100; FCM 1:25-1:100
Buffer
0.2 μm filtered solution in 20 mM MES, 100 mM NaCl, 10% Trehalose, 0.02% Tween 80, pH 6.0
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotype
IgG1
Curated Selection
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