Coagulation Factor III/Tissue Factor/CD142 Monoclonal Antibody

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Coagulation factor; TFQTL; F3; CD142; TF; TFA; CD142 antigen; coagulation factor 3; Coagulation factor III; Coagulation factor III (thromboplastin tissue factor) ; FIII; FLJ17960; HEL-S-71p; PRO1557; PRO2086; TFQTL1; Thromboplastin; Tissue factor; transferrin; Tissue Factor (TF) ; Factor III

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.