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SOD1/Superoxide Dismutase Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Abbreviation

SOD1

UniProt

P00441

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human SOD1 / Superoxide Dismutase protein

Target

HSod; HEL-S; SOD1; ALS; ALS1; HEL-S-44; IPOA; SOD; hSod1; homodimer; Superoxide dismutase [Cu-Zn]; Amyotrophic lateral sclerosis 1 adult; Cu/Zn SOD; Cu/Zn superoxide dismutase; Epididymis secretory protein Li 44; HEL S 44; Indophenoloxidase A; Mn superoxide dismutase; SOD soluble; SOD2; SODC; Superoxide dismutase 1; Superoxide dismutase 1 soluble; Superoxide dismutase Cu Zn; Superoxide dismutase cystolic

Clonality

Monoclonal

Clone

8D9

Conjugation

Unconjugated

Applications

WB; FCM; IP

Field of Research

Signal Transduction; Cell Biology; Cancer; Metabolism

Purification

Protein A

Concentration

1 mg/mL

Dilution

WB 1:500-1:1000; FCM 1:100-1:500; IP 0.2-1 μL/mg of lysate

Buffer

0.2 μm filtered solution in PBS

Shipping Conditions

Ice bag

Storage Conditions

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

16 kDa

Observed Molecular Weight

20 kDa

Isotype

IgG2b

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