SOD1/Superoxide Dismutase Monoclonal Antibody
Product Specifications
Background
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Abbreviation
SOD1
UniProt
P00441
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human SOD1 / Superoxide Dismutase protein
Target
HSod; HEL-S; SOD1; ALS; ALS1; HEL-S-44; IPOA; SOD; hSod1; homodimer; Superoxide dismutase [Cu-Zn]; Amyotrophic lateral sclerosis 1 adult; Cu/Zn SOD; Cu/Zn superoxide dismutase; Epididymis secretory protein Li 44; HEL S 44; Indophenoloxidase A; Mn superoxide dismutase; SOD soluble; SOD2; SODC; Superoxide dismutase 1; Superoxide dismutase 1 soluble; Superoxide dismutase Cu Zn; Superoxide dismutase cystolic
Clonality
Monoclonal
Clone
8D9
Conjugation
Unconjugated
Applications
WB; FCM; IP
Field of Research
Signal Transduction; Cell Biology; Cancer; Metabolism
Purification
Protein A
Concentration
1 mg/mL
Dilution
WB 1:500-1:1000; FCM 1:100-1:500; IP 0.2-1 μL/mg of lysate
Buffer
0.2 μm filtered solution in PBS
Shipping Conditions
Ice bag
Storage Conditions
This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
16 kDa
Observed Molecular Weight
20 kDa
Isotype
IgG2b
Curated Selection
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