RBP4 Monoclonal Antibody

Retinol (also known as vitamin A) is unstable and insoluble in the aqueous solution. However, retinol becomes quite stable and soluble in plasma due to its tight interaction with retinol-binding protein 4 (RBP4), also known as plasma retinol-binding protein. A prototypic member of the lipocalin superfamily, RBP4 has a beta -barrel structure with a well-defined cavity. It is secreted from the liver, a process requiring the availability of retinol. RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. The retinol-RBP4-TTR complex prevents the loss of RBP4 by filtration through the kidney and increases the stability of the retinol-RBP4 complex. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision.

RET; PRO; Retinol-binding protein; MCOPCB; RBP4; MCOPCB10; RDCCAS; RBP-4; RET4; PRBP; RBP; Retinol-binding protein 4; Plasma retinol-binding protein; Cleaved into Plasma retinol-binding protein; Plasma retinol-binding protein 1-181; Plasma retinol-binding protein 1-179; Plasma retinol-binding protein (1-176) ; PRO2222

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.