ME-344
Product Specifications
UNSPSC Description
ME-344 is a mitochondrial inhibitor. ME-344 has significant biological antitumor activity in HER2-negative breast cancer[1].
Target Antigen
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/me-344.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C2[C@H](C3=CC=C(O)C=C3)[C@H](C4=CC=C(O)C=C4)COC2=C1C
Molecular Weight
348.39
References & Citations
[1]Miguel Quintela-Fandino, et al. Randomized Phase 0/I Trial of the Mitochondrial Inhibitor ME-344 or Placebo Added to Bevacizumab in Early HER2-Negative Breast Cancer. Clin Cancer Res. 2020, 26, 1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112749/ME-344-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112749/
Clinical Information
Phase 2
CAS Number
1374524-68-1
Available Sizes
Curated Selection
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