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6-Thio-GTP

6-Thio-GTP is an analogue of GTP, and a metabolite of an immunosuppressive drug, Azathioprine.

Product Specifications

CAS Number

17670-19-8

Product Name Alternative

6-Thioguanosine-5'-triphosphate

UNSPSC

12352005

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/6-thio-gtp.html

Smiles

O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(NC(N)=N3)=S)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Molecular Formula

C10H16N5O13P3S

Molecular Weight

539.25

References & Citations

[1]Hawwa AF, et al. Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine. Br J Clin Pharmacol. 2008 Oct;66 (4) :517-28.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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