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MALAT1-IN-1

MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) [1].

Product Specifications

CAS Number

[827327-28-6]

Product Name Alternative

CP 526555-18

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/malat1-in-1.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN1C(C2=CC=C(OC)C=C2)=CN=C1NCC3=CC=CC(OC)=C3

Molecular Formula

C19H21N3O2

Molecular Weight

323.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Abulwerdi FA, et al. Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1. ACS Chem Biol. 2019 Feb 15;14 (2) :223-235.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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