Human IL-17A / CTLA-8 Protein, premium grade
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8), which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also, IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) .Furthermore, IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Product Specifications
Background
Specifications
Accession Number
Q16552-1
Expression Region
Gly 24 - Ala 155
Host
HEK293
Target
IL-17A
Conjugation
Unconjugated
Tag
Native
Source
Human
Stability
Endotoxin
0.1 EU per μg
Purity
90%
Bioactivity
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
15.1 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q16552-1
Preservative
Trehalose
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