CDK5-IN-1
CDK5-IN-1 is a potent CDK5 inhibitor with an IC50 less than 10 nM. CDK5-IN-1 is greater than 100-fold more active against CDK5 than CDK2. CDK5-IN-1 is used for kidney diseases research[1].
Product Specifications
CAS Number
[2639540-19-3]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cdk5-in-1.html
Purity
98.47
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C2C=NC(NC3=CC=C(N4N=C(CO)C=C4)C=C3F)=CC2=N1)(C5CCN(CC5)C)=O
Molecular Formula
C24H25FN6O3S
Molecular Weight
496.56
References & Citations
[1]Goran MALOJCIC, et al. Substituted 1, 6-naphthyridine inhibitors of cdk5. Patent WO2021067569.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK5
Available Sizes
Curated Selection
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