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CDK5-IN-1

CDK5-IN-1 is a potent CDK5 inhibitor with an IC50 less than 10 nM. CDK5-IN-1 is greater than 100-fold more active against CDK5 than CDK2. CDK5-IN-1 is used for kidney diseases research[1].

Product Specifications

CAS Number

2639540-19-3

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cdk5-in-1.html

Purity

98.47

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=S(C1=CC=C2C=NC(NC3=CC=C(N4N=C(CO)C=C4)C=C3F)=CC2=N1)(C5CCN(CC5)C)=O

Molecular Formula

C24H25FN6O3S

Molecular Weight

496.56

References & Citations

[1]Goran MALOJCIC, et al. Substituted 1, 6-naphthyridine inhibitors of cdk5. Patent WO2021067569.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK5

Available Sizes

Frequently Asked Questions

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