Emeramide

[1]Secor JD, et al. Novel lipid-soluble thiol-redox antioxidant and heavy metal chelator, N, N'-bis (2-mercaptoethyl) isophthalamide (NBMI) and phospholipase D-specific inhibitor, 5-fluoro-2-indolyl des-chlorohalopemide (FIPI) attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. Int J Toxicol. 2011 Dec;30 (6) :619-38.|[2]Patel RB, et al. Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-L-cysteine, and novel thiol antioxidant, N, N'-bis-2-mercaptoethyl isophthalamide. Toxicol Mech Methods. 2012 Jun;22 (5) :383-96. |[3]Gadde R, et al. N, N'bis- (2-mercaptoethyl) isophthalamide (NBMI) exerts neuroprotection against lead-induced toxicity in U-87 MG cells. Arch Toxicol. 2021 Aug;95 (8) :2643-2657.|[4]Cheng R, et al. Reversal of genetic brain iron accumulation by N, N'-bis (2-mercaptoethyl) isophthalamide, a lipophilic metal chelator, in mice. Arch Toxicol. 2022 Jul;96 (7) :1951-1962.