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BMY 42393

Product Specifications

UNSPSC Description

BMY 42393 is an orally active prostacyclin agonist which suppresses monocyte-macrophage atherogenic activity and cytokine production. BMY 42393 can be used for atherosclerosis research[1].

Target Antigen

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bmy-42393.html

Smiles

O=C(O)COC1=CC=CC(CCC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)O2)=C1

Molecular Weight

399.44

References & Citations

[1]Kowala MC, et al. Prostacyclin agonists reduce early atherosclerosis in hyperlipidemic hamsters. Octimibate and BMY 42393 suppress monocyte chemotaxis, macrophage cholesteryl ester accumulation, scavenger receptor activity, and tumor necrosis factor production. Arterioscler Thromb. 1993 Mar;13(3):435-44.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-120309/BMY-42393-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-120309/

Clinical Information

No Development Reported

CAS Number

136451-58-6

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