Purified Anti-Mouse CD105 Antibody[MJ7/18]
Product Specifications
Background
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.
Abbreviation
CD105
Gene ID
13805
UniProt
Q63961
Host
Rat
Reactivity
Mouse
Immunogen
Recombinant Human CD105 protein
Target
HHT; ORW1; AI528660; AI662476; CD105; END; Endo; Endoglin; HHT1; ORW; S-endoglin; Edg; Eng; END; HHT1; ORW; ORW1; CD 105; CD105 antigen; EGLN; FLJ41744; Osler Rendu Weber syndrome 1; RP11 228B15.2; SN6
Clonality
Monoclonal
Clone
MJ7/18
Conjugation
Unconjugated
Applications
FCM
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
PBS, pH 7.2. Contains 0.05% Proclin300.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Citation 01
https://www.mdpi.com/1422-0067/19/11/3477
Isotype
Rat IgG2a, κ
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