Purified Anti-Mouse CD105 Antibody[MJ7/18]

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

HHT; ORW1; AI528660; AI662476; CD105; END; Endo; Endoglin; HHT1; ORW; S-endoglin; Edg; Eng; END; HHT1; ORW; ORW1; CD 105; CD105 antigen; EGLN; FLJ41744; Osler Rendu Weber syndrome 1; RP11 228B15.2; SN6