7-Methoxyflavone

7-Methoxyflavone is a flavonoid compound that can be isolated from Zornia brasiliensis. 7-Methoxyflavone can bind to human serum albumin and is an aromatase inhibitor. 7-Methoxyflavone has peripheral analgesic and certain antitumor activities. 7-Methoxyflavone is effective against chemical pain but has no significant effect on thermal pain[1][2][3].

Product Specifications

CAS Number

[22395-22-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cytochrome P450

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/7-methoxyflavone.html

Purity

98.07

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C(C2=CC=CC=C2)OC3=CC(OC)=CC=C13

Molecular Formula

C16H12O3

Molecular Weight

252.27

Precautions

H302, H315, H319, H335

References & Citations

[1]da Silva AD, et al. Antinociceptive effect of 7-methoxyflavone isolated from Zornia brasiliensis. Nat Prod Res. 2013;27 (18) :1695-1699.|[2]He Q, et al. Investigation of the binding behavior of bioactive 7-methoxyflavone to human serum albumin by coupling multi-spectroscopic with computational approaches. Spectrochim Acta A Mol Biomol Spectrosc. 2023 Jan 15;285:121920.|[3]Walle T. Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass? Semin Cancer Biol. 2007 Oct;17 (5) :354-62.