PF-06649283
PF-06649283 is a drug with potential intracellular activity. The effects of PF-06649283 may be affected by factors such as cellular metabolism, protein-protein interactions, post-translational modifications, and asymmetric intracellular localization. The potency of PF-06649283 at the cellular level may show different activity compared to the recombinant enzyme, and this difference needs to be considered in the drug discovery process. Increased intracellular potency of PF-06649283 may be critical for the development of this drug as a probe or drug[1].
Product Specifications
CAS Number
[1621585-17-8]
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pf-06649283.html
Smiles
[H][C@]12[C@@](C3=CC=C(C=C3F)F)(N=C(S[C@@H]2C)N)CO[C@H](C1)C4=CC(C)=NO4
Molecular Formula
C18H19F2N3O2S
Molecular Weight
379.42
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Causes and Significance of Increased Compound Potency in Cellular or Physiological Contexts
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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