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PF-06649283

PF-06649283 is a drug with potential intracellular activity. The effects of PF-06649283 may be affected by factors such as cellular metabolism, protein-protein interactions, post-translational modifications, and asymmetric intracellular localization. The potency of PF-06649283 at the cellular level may show different activity compared to the recombinant enzyme, and this difference needs to be considered in the drug discovery process. Increased intracellular potency of PF-06649283 may be critical for the development of this drug as a probe or drug[1].

Product Specifications

CAS Number

[1621585-17-8]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Fluorescent Dye

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pf-06649283.html

Smiles

[H][C@]12[C@@](C3=CC=C(C=C3F)F)(N=C(S[C@@H]2C)N)CO[C@H](C1)C4=CC(C)=NO4

Molecular Formula

C18H19F2N3O2S

Molecular Weight

379.42

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Causes and Significance of Increased Compound Potency in Cellular or Physiological Contexts

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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