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IL-17F, Cynomolgus (HEK293, His)

IL-17F is an inflammatory homodimeric cytokine that induces many proinflammatory cytokines and chemokines. IL-17F also induces antimicrobial peptides. IL-17F plays a protective role in colon cancer development and can be used for the research of autoimmune diseases, infection and cancer[1][2]. IL-17F Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus IL-17F protein with His tag at the C-terminus and is expressed in HEK293 cells. It consists of 133 amino acids (R31-Q163) .

Product Specifications

Product Name Alternative

IL-17F Protein, Cynomolgus (HEK293, His), Cynomolgus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/il-17f-protein-cynomolgus-hek293-his.html

Smiles

RKIPKVGHTFFQKPESCPPVPEGSMKLDTGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCKHLGCINAQGKEDISMNSVPIQQETLVLRRKHQGCSVSFQLEKVLVTVGCTCVTPVVHHVQ

Molecular Formula

102118959 (Gene_ID) G7P4V0 (R31-Q163) (Accession)

Molecular Weight

Approximately 19-22 kDa, based on SDS-PAGE under reducing conditions.

References & Citations

[1]Chang SH, et al. IL-17F: regulation, signaling and function in inflammation. Cytokine. 2009 Apr;46 (1) :7-11.|[2]McGeachy MJ, et al. The IL-17 Family of Cytokines in Health and Disease. Immunity. 2019 Apr 16;50 (4) :892-906.|[3]Ferreira N, et al. IL-17A and IL-17F orchestrate macrophages to promote lung cancer. Cell Oncol (Dordr) . 2020 Aug;43 (4) :643-654.|[4]Tong Z, et al. A protective role by interleukin-17F in colon tumorigenesis. PLoS One. 2012;7 (4) :e34959.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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